Yu-Bin Ding — Endo Lab

2026

Identifying Novel Biomarkers and Therapeutic Targets for Endometriosis: Integrative Analysis of the Plasma Proteome and Genome

Mediators of inflammation ·doi:10.1155/mi/6617402

BACKGROUND: There is currently no consensus on the etiology, pathogenesis, or treatment of endometriosis (EM). The discovery of disease-associated plasma proteins with causal genetic evidence provides an opportunity to identify new EM bioma…

2025

The effect of TPOAb on pregnancy outcomes among people with polycystic ovary syndrome with euthyroidism undergoing in vitro fertilization.

Communications medicine ·doi:10.1038/s43856-025-01173-2

BackgroundPolycystic ovary syndrome (PCOS) is a complex endocrine disorder and a leading cause of infertility. When accompanied by anti-thyroid peroxidase antibodies (TPOAb), PCOS patients may face an increased risk of reproductive complica…

2023

Maternal Hepatitis B Virus Infection and Pregnancy Outcomes of Freeze-Thaw Embryo Transfer.

JAMA network open ·doi:10.1001/jamanetworkopen.2023.23495

2022

Nomogram models to predict low fertilisation rate and total fertilisation failure in patients undergoing conventional IVF cycles.

BMJ open ·doi:10.1136/bmjopen-2022-067838

ObjectivesTo establish visualised prediction models of low fertilisation rate (LFR) and total fertilisation failure (TFF) for patients in conventional in vitro fertilisation (IVF) cycles.DesignA retrospective cohort study.SettingData from A…

2012

5-aza-2'-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes.

PloS one ·doi:10.1371/journal.pone.0045364

BackgroundThe DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-CdR) incorporates into DNA and decreases DNA methylation, sparking interest in its use as a potential therapeutic agent. We aimed to determine the effects of maternal 5-aza…