Seiji Shibata

No ORCID on file · 1 paper in corpus

lab-animal 2024

Ulipristal (UPA) effects on rat ovaries: Unraveling follicle dynamics, ovulation inhibition, and safety implications for prolonged use

Reproductive toxicology (Elmsford, N.Y.) ·doi:10.1016/j.reprotox.2024.108571

Ulipristal (UPA), a selective progesterone receptor modulator, has both agonistic and antagonistic effects on progesterone receptors. UPA suppresses ovulation by inhibiting the luteinizing hormone (LH) surge from the pituitary gland; howeve…