Haijun Chen
No ORCID on file
· 2 papers in corpus
review
2025
The key players of inflammasomes and pyroptosis in sepsis-induced pathogenesis and organ dysfunction
Pyroptosis is an inflammatory form of cell death involving caspase-1 or caspase-4/5/11, initiated by inflammasomes or cytoplasmic endotoxins as part of the immune defense. It is specifically characterized by Gasdermin-mediated pore formatio…
lab-animal
2014
Mifepristone (RU486) is marketed and used widely by women as an abortifacient, and experimentally for psychotic depression and anticancer treatments. After administration, metapristone is found to be the most predominant metabolite of mifep…