Simiao Yan

No ORCID on file · 4 papers in corpus · active 2023-2026

Study types

  • article 3
  • preprint 1

Condition tags

  • adenomyosis 4
  • endometriosis 1
article 2026
Inhibition of Sonic Hedgehog signaling pathway by GANT61 alleviates adenomyosis by suppressing epithelial-to-mesenchymal transition, cell migration and proliferation
Tissue & cell ·doi:10.1016/j.tice.2026.103581

Adenomyosis (ADM) is a benign condition associated with various gynecological disorders. However, effective treatment options are limited, highlighting the urgent need for novel therapeutic targets. This study identified abnormal activation…

article 2023
Abnormal activation of the Wnt3a/β-catenin signaling pathway promotes the expression of T-box transcription factor 3(TBX3) and the epithelial-mesenchymal transition pathway to mediate the occurrence of adenomyosis
Molecular biology reports ·doi:10.1007/s11033-023-08870-y

BACKGROUND: T-box transcription factor 3(TBX3) is a transcription factor that can regulate cell proliferation, apoptosis, invasion, and migration in different tumor cells; however, its role in adenomyosis (ADM) has not been previously studi…

preprint 2023
Abnormal activation of the Wnt3a/β-catenin signaling pathway promotes the expression of TBX3 and the EMT pathway to mediate the occurrence of adenomyosis
·doi:10.21203/rs.3.rs-2803345/v1

Abstract Background TBX3 is a transcription factor that can regulate cell proliferation, apoptosis, invasion, and migration in different tumor cells; however, its role in adenomyosis (ADM) has not been previously studied. Some of ADM’s path…

article 2023
The Inactivation of Hippo Signaling Pathway Promotes the Development of Adenomyosis by Regulating EMT, Proliferation, and Apoptosis of Cells
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-023-01189-w

Adenomyosis is a benign gynecological disease. The pathogenesis of adenomyosis is still unclear. The Hippo signaling pathway is highly conserved in vivo and associated with endometriosis and various cancers. Our objective was to study the e…