Masahiro Kanai

ORCID: 0000-0001-5165-4408 · 4 papers in corpus
article 2025
Small Intestinal Stricture With Intense 18F-FDG PET Activity Caused by Endometriosis
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association ·doi:10.1016/j.cgh.2025.09.012
2024
Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles.
Nature genetics ·doi:10.1038/s41588-024-01682-1

Translating genome-wide association study (GWAS) loci into causal variants and genes requires accurate cell-type-specific enhancer-gene maps from disease-relevant tissues. Building enhancer-gene maps is essential but challenging with curren…

2023
FinnGen provides genetic insights from a well-phenotyped isolated population.
Nature ·doi:10.1038/s41586-022-05473-8

Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%). These variants survived the founding …

2020
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
Nature genetics ·doi:10.1038/s41588-020-0640-3

The overwhelming majority of participants in current genetic studies are of European ancestry. To elucidate disease biology in the East Asian population, we conducted a genome-wide association study (GWAS) with 212,453 Japanese individuals …