Büchler MW

No ORCID on file · 3 papers in corpus · active 2003-2020
2020
Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis.
Cell death & disease ·doi:10.1038/s41419-020-03050-3

Chronic pancreatitis (CP) is associated with elevated plasma levels of bacterial lipopolysaccharide (LPS) and we have demonstrated reduced acinar cell autophagy in human CP tissue. Therefore, we investigated the role of autophagy in experim…

2011
Surgery for locally recurrent rectal cancer in the era of total mesorectal excision: is there still a chance for cure?
Annals of surgery ·doi:10.1097/sla.0b013e3182096d4f

ObjectiveTo evaluate the perioperative outcome and long-term survival of patients who underwent surgical resection for recurrent rectal cancer within a multimodal approach in the era of total mesorectal excision (TME).BackgroundIntroduction…

2003
COMP is selectively up-regulated in degenerating acinar cells in chronic pancreatitis and in chronic-pancreatitis-like lesions in pancreatic cancer.
Scandinavian journal of gastroenterology ·doi:10.1080/00365520310000717

BackgroundChronic pancreatitis (CP) is an inflammatory disease of the pancreas characterized histomorphologically by progressive development of fibrosis and atrophy of the pancreatic parenchyma. Cartilage oligomeric matrix protein (COMP) is…