William F. Crowley

No ORCID on file · 3 papers in corpus · active 1991-2010

Study types

  • other 2
  • article 1

Condition tags

  • endometriosis 3
  • infertility 1
other 2010
A high-throughput small-molecule ligand screen targeted to agonists and antagonists of the G-protein-coupled receptor GPR54
Journal of biomolecular screening ·doi:10.1177/1087057110369701

Recent data have shown that the G-protein-coupled receptor GPR54 (also known as KiSS-1 receptor) regulates GnRH release from the hypothalamus. This essential role of GPR54 in controlling the hypothalamic-pituitary-gonadal axis makes it an a…

other 2006
Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): a finding with therapeutic implications
Endocrinology ·doi:10.1210/en.2005-1550

The effect of continuous administration of the C-terminal fragment of metastin, the ligand for the G protein-coupled receptor, GPR54, on GnRH-induced LH secretion was examined in three agonadal, juvenile male monkeys whose responsiveness to…

article 1991
Gonadotropin-Releasing Hormone and Its Analogues
·doi:10.1056/nejm199101103240205

RESEARCH into the neuroendocrine control of reproduction by gonadotropin-releasing hormone (GnRH) has witnessed a remarkable two decades. From the isolation and chemical characterization of GnRH in 1971 through the awarding of the Nobel Pri…