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Sphingolipids are important constituents of cell membranes, which play key roles as regulatory molecules for various cellular functions. Sphingosine-1-phosphate produced by sphingosine kinase 1 (SPHK1) promotes cell proliferation, regulates…
Membrane proteins of the claudin superfamily are important components of cellular tight and adherens junctions. Although their exact function remains unclear, these proteins may play a role in tissue remodeling, a process which is associate…
Cytokeratins are a multigene family of polypeptides expressed in distinct combinations along the various routes of epithelial differentiation. In endometrial cancer and cervical intraepithelial neoplasia/cervical squamous cell carcinoma, th…
OBJECTIVE: To characterize the expression of WNT7A in human eutopic and ectopic endometrium. DESIGN: Experimental study using real-time polymerase chain reaction, laser microdissection, in situ hybridization, and immunofluorescence. SETTI…
BACKGROUND: The metalloproteinases (MMPs) are a family of proteolytic enzymes involved in tissue remodeling and cell migration. Endometrial tissue remodeling proceeds during the menstrual cycle and requires a temporary and spatially balance…