Ostrowska-Leśko M

2025

Advances in Systemic Therapy for Ovarian Cancer Over the Past Decade: A Clinical and Molecular Perspective.

Medical science monitor : international medical journal of experimental and clinical research ·doi:10.12659/msm.949526

Epithelial ovarian cancer (EOC) remains a leading cause of gynecologic cancer mortality, with high rates of recurrence and chemoresistance. Advances in understanding the molecular biology of EOC, particularly BRCA mutations and homologous r…

2025

Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series.

Virchows Archiv : an international journal of pathology ·doi:10.1007/s00428-025-04026-4

Low-grade endometrial stromal sarcoma (LG-ESS) can present diagnostic challenges, due to its overlapping morphological features with other uterine mesenchymal tumors. Misdiagnosis rates remain significant, and immunohistochemical data for L…

2022

Integration of local and systemic immunity in ovarian cancer: Implications for immunotherapy.

Frontiers in immunology ·doi:10.3389/fimmu.2022.1018256

Cancer is a disease that induces many local and systemic changes in immunity. The difficult nature of ovarian cancer stems from the lack of characteristic symptoms that contributes to a delayed diagnosis and treatment. Despite the enormous …