Orr, Natasha L.

A key clinical problem is identifying the endometriosis patient whose pain is complicated by central nervous system sensitization, where conventional gynecologic treatment (e.g. hormonal therapy or surgery) may not completely alleviate the …

Background: Endometriosis is a complex condition that can negatively affect a woman’s quality of life, including her sleep. This study aims to assess the multifactorial variables associated with poorer quality of sleep in women with endomet…

Background. Deep dyspareunia, a common symptom in endometriosis, has previously been associated with bladder or pelvic floor tenderness (BPFT), which suggests a role for central nervous system sensitization. The Central Sensitization Invent…

Background. The etiology of endometriosis-associated deep dyspareunia may include direct endometriosis-specific factors (e.g., Stage or invasiveness of disease) and/or indirect contributors such as bladder/pelvic floor dysfunction (e.g., re…

Introduction: Dyspareunia has been traditionally divided into superficial (introital) dyspareunia and deep dyspareunia (pain with deep penetration). While deep dyspareunia can co-exist with a variety of conditions, recent work in endometrio…