Marian J E Mourits

No ORCID on file · 4 papers in corpus
lab-animal 2025
Nature genetics ·doi:10.1038/s41588-025-02308-w

Mutagenic processes and clonal selection contribute to the development of therapy-associated secondary neoplasms, a known complication of cancer treatment. The association between tamoxifen therapy and secondary uterine cancers is uncommon …

observational 2024
JACC. CardioOncology ·doi:10.1016/j.jaccao.2024.09.011

BACKGROUND: Premenopausal risk-reducing salpingo-oophorectomy (RRSO) in women at high familial risk of ovarian cancer leads to immediate menopause. Although early natural menopause is associated with increased cardiovascular disease risk, e…

nonrandomized-trial 2021
JAMA oncology ·doi:10.1001/jamaoncol.2021.1590

IMPORTANCE: Most women with a BRCA1/2 pathogenic variant undergo premature menopause with potential short- and long-term morbidity due to the current method of ovarian carcinoma prevention: risk-reducing salpingo-oophorectomy (RRSO). Becaus…

observational 2020
Rheumatology (Oxford, England) ·doi:10.1093/rheumatology/keaa017

OBJECTIVE: The aim was to study clinical, histopathological and immunological changes in the vagina and cervix of women with primary SS, which might explain vaginal dryness. METHODS: We included 10 pre-menopausal female primary SS patients…