Nergis Özlem Kılıç

2025

CCNA2 and CCNB3 as Early Potential Molecular Candidates of Oocyte Maturation in Cumulus-Oophorous Complex Cells from Follicular Fluid.

Diagnostics (Basel, Switzerland) ·doi:10.3390/diagnostics15202658

Background/Objectives: Oocyte maturation is a process involving both nuclear and cytoplasmic development regulated by epigenetic changes in gene expression. Cyclin-B3 (CCNB3) and cyclin-A2 (CCNA2) genes are thought to be involved in oocyte …

article 2025

Fluid biopsies for in vitro fertilization: Non‑invasive innovations (Review)

Medicine international ·doi:10.3892/mi.2025.290

fertilization (IVF) and support the development of personalized, sustainable fertility treatments. The present review aimed to summarize and critically evaluate developments in non-invasive liquid biopsy techniques in IVF, highlight their c…

2024

Molecular Markers in Embryo Non-Development: Analysis of Gene Expressions (Ki-67, hTERT, HIF-1α) in Spent Embryo Culture Medium.

Cells ·doi:10.3390/cells13242093

An embryo culture medium is a specialized set of ambient conditions, technological equipment, and nutrients that embryos require to grow properly. We aimed to investigate the Ki-67, hTERT, and HIF-1α gene expression differences between deve…