Anna P. Ponnampalam

BACKGROUND: Endometriosis is a chronic condition where patients face challenging care journeys. There is minimal literature regarding perspectives of nurses on their approach to caring for endometriosis patients. AIMS: This paper assesses …

BACKGROUND: General practitioners (GPs) are gatekeepers to specialist attention for endometriosis in the public system in Aotearoa New Zealand (Aotearoa-NZ). Their perspective of the endometriosis care landscape in Aotearoa-NZ has not been …

Currently, our understanding of hormonal regulation within the female reproductive system is largely based on our knowledge of estrogen and progesterone signalling. However, while the important functions of androgens in male physiology are …

Steroid hormones govern the complex, cyclic changes of the endometrium, predominantly through their receptors. An interplay between steroid hormones and epigenetic mechanisms controls the dynamic endometrial gene regulation. Abnormalities i…

Histone acetylation is a critical epigenetic modification that changes chromatin architecture and regulates gene expression by opening or closing the chromatin structure. It plays an essential role in cell cycle progression and differentiat…

Endometriosis affects 10% of reproductive-aged women. It is characterized by the growth of the endometrium, outside the uterus and is associated with infertility and chronic abdominal pain. Lack of noninvasive diagnostic tools and early scr…