Christoph Trautwein

article 2026

Additional file 1 of NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.32723643

Supplementary Material 1: Table S1. Table S1 – Annotation of the abbreviations used by the IVDr lipoprotein profiling analysis.

article 2026

Additional file 1 of NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.32723643.v1

Supplementary Material 1: Table S1. Table S1 – Annotation of the abbreviations used by the IVDr lipoprotein profiling analysis.

dataset 2026

Additional file 2 of NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.32723646.v1

Supplementary Material 2: Tables S2-S3. Table S2 – Assay-specific lower limits of quantitation (LLOQ, pg/mL) used to define missing cytokine values. Table S3 – Membership of non-grey WGCNA modules identified in the signed network analysis.

dataset 2026

Additional file 2 of NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.32723646

Supplementary Material 2: Tables S2-S3. Table S2 – Assay-specific lower limits of quantitation (LLOQ, pg/mL) used to define missing cytokine values. Table S3 – Membership of non-grey WGCNA modules identified in the signed network analysis.

article 2026

Additional file 4 of NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.32723652.v1

Supplementary Material 4: Table S4A. Table S4A – Exploratory nominal cytokine-metabolite and cytokine-lipoprotein associations (Spearman raw p < 0.05) in the endometriosis-only and sensitivity cohorts.

article 2026

Additional file 4 of NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.32723652

Supplementary Material 4: Table S4A. Table S4A – Exploratory nominal cytokine-metabolite and cytokine-lipoprotein associations (Spearman raw p < 0.05) in the endometriosis-only and sensitivity cohorts.

article 2026

Additional file 5 of NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.32723655

Supplementary Material 5: Table S4B. Table S4B – FDR-significant cytokine-cytokine correlations in the endometriosis-only and sensitivity cohorts.

article 2026

Additional file 5 of NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.32723655.v1

Supplementary Material 5: Table S4B. Table S4B – FDR-significant cytokine-cytokine correlations in the endometriosis-only and sensitivity cohorts.

other 2026

NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.c.8544015.v1

Abstract Background Reliable non-invasive biomarkers for endometriosis remain unavailable in routine practice, and their translational value depends on performance in symptomatic referral populations rather than only against healthy control…

article 2026

NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

BMC medicine ·doi:10.1186/s12916-026-04999-2

BACKGROUND: Reliable non-invasive biomarkers for endometriosis remain unavailable in routine practice, and their translational value depends on performance in symptomatic referral populations rather than only against healthy controls. We ev…

other 2026

NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals

·doi:10.6084/m9.figshare.c.8544015

Abstract Background Reliable non-invasive biomarkers for endometriosis remain unavailable in routine practice, and their translational value depends on performance in symptomatic referral populations rather than only against healthy control…

2025

Identification and impact of microbiota-derived metabolites in ascites of ovarian and gastrointestinal cancer.

Cancer & metabolism ·doi:10.1186/s40170-025-00391-5

BackgroundMalignant ascites is a common complication of advanced ovarian cancer (OC) and gastrointestinal cancer (GI), significantly impacting metastasis, quality of life, and survival. Increased intestinal permeability can lead to blood or…

2022

Acidic ascites inhibits ovarian cancer cell proliferation and correlates with the metabolomic, lipidomic and inflammatory phenotype of human patients.

Journal of translational medicine ·doi:10.1186/s12967-022-03763-3

BackgroundThe poor prognosis of ovarian cancer patients is strongly related to peritoneal metastasis with the production of malignant ascites. However, it remains largely unclear how ascites in the peritoneal cavity influences tumor metabol…