Koestler DC

ORCID: 0000-0002-0598-0146 · 3 papers in corpus · active 2013-2025
2025
Translational Implications of The Gut Microbiome in Women with A Benign or Malignant Pelvic Mass.
Annals of obstetrics and gynecology

ObjectiveThe role of the gut microbiome in non-gastrointestinal cancers has generated growing interest in the field of gynecologic oncology. Our objective was to characterize the gut microbiome in women with a pelvic mass suspicious for ova…

2014
Methylation of leukocyte DNA and ovarian cancer: relationships with disease status and outcome.
BMC medical genomics ·doi:10.1186/1755-8794-7-21

BackgroundGenome-wide interrogation of DNA methylation (DNAm) in blood-derived leukocytes has become feasible with the advent of CpG genotyping arrays. In epithelial ovarian cancer (EOC), one report found substantial DNAm differences betwee…

2013
Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel.
Human molecular genetics ·doi:10.1093/hmg/ddt160

Ovarian cancer remains the leading cause of death in women with gynecologic malignancies, despite surgical advances and the development of more effective chemotherapeutics. As increasing evidence indicates that clear-cell ovarian cancer may…