Liu Y

Epidemiological inconsistencies currently obscure the causal link between polychlorinated biphenyls (PCBs) and breast cancer. This review synthesizes multi-disciplinary evidence to characterize PCBs not as passive exposure correlates but as…

Background: Postmenopausal uterine torsion is an extremely rare gynecological emergency that is often challenging to diagnose preoperatively because of its atypical presentation. This case is particularly noteworthy for a 10-year history of…

Endometriosis-associated ovarian cancer (EAOC) is a rare subtype of ovarian cancer arising from the malignant transformation of endometriosis (EMS). Despite growing clinical awareness, its underlying pathogenic mechanisms are not fully unde…

This Correspondence is a formal response to the Comment by Dr. Machado regarding our publication "Creatine Promotes Endometriosis by Inducing Ferroptosis Resistance via Suppression of PrP." We address several conceptual concerns raised in t…

PurposeInfants born after assisted reproductive technology (ART) have more adverse health outcomes than spontaneously conceived infants. Evidence on the impact of ART on the offspring's visual system, particularly refractive errors (REs), r…

Endometriosis is characterized by progressive fibrosis and limited therapeutic options. Cuproptosis, a copper-dependent form of regulated cell death, has been implicated in multiple pathological conditions, but its relevance to fibroblast-m…

BACKGROUND: Adenomyosis (AM) is a common gynecological disorder in reproductive-age women, with impaired endometrial receptivity as a key contributor to infertility. However, a comprehensive single-cell atlas of the eutopic endometrium duri…

BackgroundThe incidence of malignant tumors/precancerous lesions is rising, yet their impact on pregnancy outcomes in women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) remains unclear.MethodsA single-center…

PurposeAcute pancreatitis (AP) is an inflammatory disorder with rising global incidence. Substantial progress in elucidating AP pathophysiology has been achieved over the past two decades. This study aims to assess the evolution of AP patho…

BackgroundProtein palmitoylation is a significant post-translational modification that influences protein stability, localization, and signaling through the addition of palmitoyl groups to cysteine, serine/threonine, or lysine residues. It …

OBJECTIVE: To compare dietary preparation durations and evaluate optimal diet types before high-intensity focused ultrasound (HIFU) treatment. MATERIALS AND METHODS: Five hundred patients with uterine fibroids or adenomyosis undergoing HIF…

Filamentous fungi exhibit high heavy metal resistance; elucidating their resistance mechanisms is of practical importance for fungal utilization and for engineering other microorganisms. However, the molecular basis of copper tolerance in f…

BACKGROUND: To analyze trends in surgical approach stratified by Body Mass Index (BMI) among women undergoing hysterectomy for benign indications in the United States and to compare clinical outcomes in morbidly obese patients (BMI > 40 kg/…

ObjectiveTo evaluate whether vitamin D supplementation improves live birth rates in women with polycystic ovary syndrome undergoing in vitro fertilisation.DesignMulticentre, double blind, placebo controlled, randomised clinical trial.Settin…

BackgroundTraditional research on the female reproductive tract (FRT) microbiome has focused on the dominance of bacteria, particularly Lactobacillus, as a marker of health. This bacteriocentric paradigm, however, cannot fully explain clini…

BackgroundImmature teratoma is a malignant tumor and accounts for 1%-3% of ovary teratoma. The objective of this study was to find the potential single nucleotide polymorphisms (SNPs), copy number variations (CNVs) and drug targets in the i…

BackgroundHepatocellular carcinoma (HCC) mainly develops in cases of fibrosis and cirrhosis and is accompanied by intestinal flora disorder. HCC also affects CD8+ T cell immune function. 5,7-Dimethoxyflavone (DMF), an active flavonoid with …

Introduction Uterine rupture (UR) during pregnancy refers to a disruption of the uterine wall involving the myometrium and serosa that occurs in association with pregnancy. The global incidence of UR is rising, and this condition can lead t…

Dichloroacetate (DCA), as a pan-inhibitor of pyruvate dehydrogenase kinase, plays a crucial role in energy metabolism and mitochondrial function. DCA decreases lactic acid synthesis, enhances mitochondrial oxidative phosphorylation, and reg…

PurposeThe application of narrow-band imaging for missed early miscarriage treatment remains unclear. This study determined the application advantages of NBI combined with hysteroscopic 7Fr cold knife embryo removal for treating missed earl…

BackgroundThis study aims to investigate the efficacy and safety of dexmedetomidine in treating postoperative acute pain through a clinical randomized controlled trial.MethodsThis study selected 165 patients who underwent general anesthesia…

IntroductionThe burden of gynaecological diseases is increasing globally, affecting women's health, quality of life and fertility. Improving the quality of gynaecological care will enhance patient recovery and improve outcomes of gynaecolog…

BackgroundWhile metabolic syndrome and obesity are established risk factors for infertility, previous studies have neglected age-specific analyses and nonlinear associations, particularly in women aged 20-45 years, a critical demographic fo…

BackgroundOrganochlorine pesticides (OCPs) are extensively dispersed throughout the environment, which potentially have harmful impacts on the female reproductive system. Therefore, the purpose of this study was to clarify the association b…