Infertility is common, affecting up to 15 percent of couples [1]. One-third of infertility is attributed to a female factor, whereas 20 percent of infertility is attributed to a male factor. In up to 20–40 percent of cases, there are both a…
Endometriosis is a common condition in women that causes chronic pain and infertility and is associated with an elevated risk of ovarian cancer. We profiled transcriptomes of >370,000 individual cells from endometriomas (n = 8), endometrios…
Abstract Endometriosis is a common, benign condition characterized by extensive heterogeneity in lesion appearance and patient symptoms. We profiled transcriptomes of 207,949 individual cells from endometriomata (n=7), extra-ovarian endomet…
PurposeTo determine the utility of the endometrial receptivity analysis (ERA) in women with prior failed embryo transfers (ET).MethodsThis was a retrospective study of patients who underwent an ERA test with a subsequent frozen ET. Women we…
CONTEXT: Infertility affects 10% of the reproductive-age population. Even the most successful treatments such as assisted reproductive technologies still result in failed implantation. In addition, adverse pregnancy outcomes associated with…