Mayerle J

ORCID: 0000-0002-3666-6459 · 4 papers in corpus
2022
[Overview of relevant clinical recommendations from the new S3 guidelines on acute and chronic pancreatitis].
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen ·doi:10.1007/s00104-022-01598-8

Acute pancreatitis is a primary sterile inflammation of the pancreas, which is characterized by an unphysiological enzyme activation. This leads to an inflammatory reaction with edema, vascular damage and cell decay. The first German interd…

2021
A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies.
Journal of inflammation research ·doi:10.2147/jir.s304787

PurposeAlthough strongly related, the pathophysiological effect of the N34S mutation in the serine protease inhibitor Kazal type 1 (SPINK1) in chronic pancreatitis is still unknown. In this study, we investigate the conformational space of …

2017
United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU).
United European gastroenterology journal ·doi:10.1177/2050640616684695

BackgroundThere have been substantial improvements in the management of chronic pancreatitis, leading to the publication of several national guidelines during recent years. In collaboration with United European Gastroenterology, the working…

2015
Genetic susceptibility factors for alcohol-induced chronic pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] ·doi:10.1016/j.pan.2015.05.476

Chronic pancreatitis is a progressive inflammatory disease of the pancreas and frequently associated with immoderate alcohol consumption. Since only a small proportion of alcoholics eventually develop chronic pancreatitis genetic susceptibi…