Li L

ORCID: 0000-0001-5873-7089 · 371 papers in corpus
2025
Medicine ·doi:10.1097/md.0000000000045879

Primary dysmenorrhea (PD) is one of the common gynaecological disorders, which significantly affects the physical and mental health of women of reproductive age. Shenghua Decoction (SHD) is a classic formula for treating gynaecological diso…

other 2025
Archives of gynecology and obstetrics ·doi:10.1007/s00404-025-08170-9

PURPOSE: The aim of this study was to summarize and analyze the incidence, underlying causes and related risk factors of misdiagnosis in patients with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA) syndrome. METHODS: This is …

other 2025
iScience ·doi:10.1016/j.isci.2025.113113

Conventional treatments for advanced endometriosis often have limited efficacy due to chemotherapy resistance, recurrence, and metastasis. This study analyzed clinical specimens to investigate the role of NXF1 in endometrial cancer (ECa) pr…

other 2025
Natural product research ·doi:10.1080/14786419.2023.2294113

Previous research has indicated that Polyphyllin I (PPI) possesses potent anticancer properties. However, its impact on endometriosis remains unexplored. This study aims to investigate the inhibitory effects of PPI on ectopic endometrial st…

2025
BMJ (Clinical research ed.) ·doi:10.1136/bmj-2025-084050

ObjectiveTo assess the efficacy of preimplantation genetic testing for aneuploidies (PGT-A) compared to intracytoplasmic sperm injection (ICSI) alone in couples undergoing ICSI treatment because of severe male infertility.DesignMulticentre,…

review 2025
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-024-01745-y

High intensity focused ultrasound (HIFU) is an effective and safe non-invasive treatment method, widely used in the treatment of uterine fibroids and adenomyosis in the field of gynecology. The side effects in HIFU is low in incidence and m…

2025
Acta pharmaceutica Sinica. B ·doi:10.1016/j.apsb.2025.10.026

Peptide- and protein-based therapeutics offer realized and potential benefits to health, due to their potent bioactivity, high specificity, and favorable safety characteristics. However, their widespread clinical application is constrained …

2025
STAR protocols ·doi:10.1016/j.xpro.2024.103579

Non-invasive prenatal testing (NIPT) not only enables the detection of chromosomal anomalies in fetuses but also generates vast amounts of ultra-low-depth sequencing data, which can be leveraged for population genomic studies. Here, we pres…

2025
Reproduction & fertility ·doi:10.1530/raf-24-0088

This study reveals the association between gene copy number variants (CNVs) and integrin expression in endometrial tissue, especially focusing on patients with repeated implantation failure and unexplained infertility. The CNV expression, i…

2025
Current genomics ·doi:10.2174/0113892029345945241125064704

IntroductionRecent investigations have underscored the importance of long non-coding RNAs (lncRNAs), which exhibit more specific expression in tissues and cells than mRNA and are involved in gene regulation during development, pathology, an…

article 2025
BMC women's health ·doi:10.1186/s12905-025-03700-8

BACKGROUND: Adenomyosis is a common gynecological disorder characterized by the invasion of endometrial tissue into the myometrium, resulting in severe dysmenorrhea and menorrhagia. This study aimed to explore the role of SMOC2 (SPARC relat…

2025
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-025-03422-8

PurposeThis study aims to summarize and analyze the existing research on anxiety and depression within the field of assisted reproduction technology, exploring current hotspots, emerging frontiers, and trends, while offering insights for fu…

2025
NPJ biofilms and microbiomes ·doi:10.1038/s41522-025-00695-w

Chronic pancreatitis (CP) is characterized by irreversible fibrotic destruction and impaired pancreatic function. CP disrupts lipid metabolism and causes the imbalance of gut microbiota which in turn exacerbates pancreatic fibrosis. Statins…

2025
Journal of robotic surgery ·doi:10.1007/s11701-025-02422-1

Performing robotic hysterectomy (RH) on large uteri is a significant challenge. This study aims to investigate the impact of various risk factors on surgical outcomes and to identify the most effective surgical approach for performing RH on…

2025
The journal of pathology. Clinical research ·doi:10.1002/2056-4538.70040

In this study, we explored the genomic underpinnings of synchronous endometrial and ovarian/fallopian tube carcinoma (SEOC) and synchronous cervical and ovarian/fallopian tube carcinoma (SCOC), focusing on their clonal relationships to disc…

2025
PloS one ·doi:10.1371/journal.pone.0327831

BackgroundAlcohol use is a major risk factor for pancreatitis and global mortality. Despite its impact, comprehensive analyses of the burden across regions and sociodemographic strata remain scarce. This study examines global trends (1990-2…

2025
European journal of medical research ·doi:10.1186/s40001-025-03506-2

BackgroundHysteroscopy is a common procedure in assisted reproductive technology (ART) and serves as the gold standard for diagnosing and treating uterine cavity lesions. However, there is currently a lack of research on the impact of opera…

2025
MedComm ·doi:10.1002/mco2.70296

Currently, there are many diseases worldwide that seriously affect women's health. Among these, gestational disorders and female cancers such as ovarian cancer are particularly notable for their high morbidity and mortality rates. Over the …

2025
Journal of clinical medicine ·doi:10.3390/jcm14144970

Background: The stress hyperglycemia ratio (SHR) has emerged as a promising biomarker for assessing stress-induced hyperglycemia (SH) but has not been evaluated in patients with acute pancreatitis (AP). This study investigates the role of t…

2024
Heliyon ·doi:10.1016/j.heliyon.2024.e28442

BackgroundAccording to statistics, ovarian cancer (OV) is the most prevalent type of gynecologic malignancy and has the highest mortality rate of all gynecologic tumors. Although several studies have shown that oxidative stress (OS) contrib…

2024
Medicine ·doi:10.1097/md.0000000000040406

To explore the factors influencing the clinical pregnancy rate in the Reproductive Center of the Affiliated Hospital of North Sichuan Medical College in the second cycle, a retrospective analysis of the clinical data of 175 patients who und…

2024
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1278504

ObjectiveThe objective was to analyze the impact of the uterine artery pulsatility index (PI) on pregnancy outcomes by measuring uterine artery blood flow on the day of endometrial transformation in patients undergoing frozen-thawed embryo …

case-report 2024
Frontiers in neurology ·doi:10.3389/fneur.2024.1360164

INTRODUCTION: Anti-sulfatide antibodies are key biomarkers for the diagnosis of Guillain-Barré syndrome (GBS). However, case reports on anti-sulfatide antibody-related GBS are rare, particularly for atypical cases. CASE DESCRIPTION CASE 1:…

2024
Frontiers in oncology ·doi:10.3389/fonc.2024.1432970

BackgroundsAdvanced ovarian cancer is frequently accompanied by extensive peritoneal metastasis, complicating surgical interventions. This study aims to explore the application of 3D reconstruction and 3D printing technology in the treatmen…

2024
BMC women's health ·doi:10.1186/s12905-024-03198-6

ObjectiveTo investigate the association between caesarean scar defects and abnormal uterine bleeding through systematic literature review.MethodsPubMed, Web of Science, Cochrane Library and Embase databases were searched based on PRISMA 202…