Li L

ORCID: 0000-0001-5873-7089 · 378 papers in corpus
observational 2019
Experimental and therapeutic medicine ·doi:10.3892/etm.2019.7935

This study aimed to investigate the clinical factors affecting pregnancy rates following the surgical removal of intrauterine adhesions (IUAs) and subsequent in vitro fertilization and embryo transfer (IVF-ET). We retrospectively evaluated …

observational 2019
Frontiers in endocrinology ·doi:10.3389/fendo.2019.00067

Objective: To investigate whether circulating LH levels could be used as an indicator for the timing of antagonist addition in GnRH antagonist protocol. Design: Retrospective cohort study. Setting: University-based hospital. Patients: A tot…

other 2019
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-019-0538-z

BACKGROUND: Previous work demonstrated that there are numerous miRNAs in human follicular fluids, some of which are associated with reproductive diseases. In the current study, we sought to determine whether microRNAs (miRNAs) in the follic…

other 2019
Chinese medical journal ·doi:10.1097/cm9.0000000000000195

To the Editor: Endometriosis refers to the endometrial tissue (interstitial substance and gland) with growth function occurring in the uterine lining of uterine cavity and the places outside myometrium. It often leads to pain, infertility, …

nonrandomized-trial 2019
Scientific reports ·doi:10.1038/s41598-019-41499-1

Progesterone elevation (PE) on the day of hCG trigger is associated with decreased pregnancy outcome in fresh cycles. Evidence for this comes from overall patient estimates that mostly ignore different ovarian responses. To compare the impa…

review 2019
Journal of Cancer ·doi:10.7150/jca.29421

Cancer cells are usually exposed to stressful environments, such as hypoxia, nutrient deprivation, and other metabolic dysfunctional regulation, leading to continuous endoplasmic reticulum (ER) stress. As the most conserved branch among the…

diagnostic-accuracy 2018
Oncology letters ·doi:10.3892/ol.2018.8805

Magnetic resonance imaging exhibits high sensitivity but low specificity for breast cancer. The present study aimed to investigate whether combining morphology, texture features and kinetic features with diffusion-weighted imaging using qua…

2018
Molecular medicine reports ·doi:10.3892/mmr.2018.9346

The aim of the present study was to investigate the effects of Toll‑like receptor (TLR) 9 and CpG oligodeoxynucleotide (CpG‑ODN)1826 on sodium taurocholate‑induced acute pancreatitis (AP) rats at different time points. Pathological examinat…

diagnostic-accuracy 2018
Science translational medicine ·doi:10.1126/scitranslmed.aap8793

We report the detection of endometrial and ovarian cancers based on genetic analyses of DNA recovered from the fluids obtained during a routine Papanicolaou (Pap) test. The new test, called PapSEEK, incorporates assays for mutations in 18 g…

other 2018
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-017-0319-5

BACKGROUND: The etiology and pathophysiology of endometriosis remain unclear. Accumulating evidence suggests that aberrant microRNA (miRNA) and transcription factor (TF) expression may be involved in the pathogenesis and development of endo…

lab-animal 2018
Cell cycle (Georgetown, Tex.) ·doi:10.1080/15384101.2018.1489179

Oocyte is arrested at metaphase of the second meiosis until fertilization switching on [Ca2+]i oscillations. Oocyte activation inefficiency is the most challenging problem for failed fertilization and embryonic development. Mitochondrial fu…

2018
Experimental and therapeutic medicine ·doi:10.3892/etm.2018.6577

Severe acute pancreatitis (SAP) is a serious systemic disease with high mortality. Ulinastatin is a drug widely used for patients with SAP and multiple organ failure syndrome. The present study aimed to investigate the capacity of the serum…

observational 2017
Experimental and therapeutic medicine ·doi:10.3892/etm.2017.5390

Endometriosis (EM) is associated with oxidative stress. Advanced oxidation protein products (AOPPs) are novel markers of oxidative stress, which serve an important role as an inflammatory mediator in various chronic diseases. In order to ex…

lab-animal 2017
Stem cells international ·doi:10.1155/2017/4794827

Human endometrial tissue has become an attractive source of mesenchymal stem cells (MSCs) for cell-based therapies because these MSCs can be easily harvested and have tumour tropism as well as reduced immunogenic and inflammatory properties…

case-report 2017
Oncology letters ·doi:10.3892/ol.2017.5737

Intramural pregnancy is a rare type of ectopic pregnancy with an unclear etiology. It may be associated with uterine wall injury and/or abnormal uterine conditions, such as adenomyosis, in certain cases. In the present report, a case of int…

diagnostic-accuracy 2017
Cancer biomarkers : section A of Disease markers ·doi:10.3233/cbm-170305

BACKGROUND: Early detection and differentiation diagnosis of a pelvic mass (PM) is crucial in improving the prognosis of patients with epithelial ovarian cancer (EOC). C-C motif chemokine ligand 18 (CCL18) was reported as a chemokine-mediat…

other 2017
Molecular medicine reports ·doi:10.3892/mmr.2017.6422

Pemphigus is an autoimmune disease that causes blisters and erosions in the skin and mucous membranes. The development of pemphigus is associated with the imbalance of T‑cell and humoral responses. MicroRNAs (miRNAs) can regulate many cell …

lab-animal 2017
Oncotarget ·doi:10.18632/oncotarget.16523

Aerobic glycolysis is essential for tumor growth and survival. Activation of multiple carcinogenic signals contributes to metabolism reprogramming during malignant transformation of cancer. Recently nitric oxide has been noted to promote gl…

other 2016
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2016.05.005

OBJECTIVE: To investigate treatment effects of levonorgestrel-releasing intrauterine system (LNG-IUS) for adenomyosis with severe dysmenorrhea in a prospective cohort study. METHODS: From December 2006 to December 2014, patients of symptom…

other 2016
Zhonghua yi xue za zhi ·doi:10.3760/cma.j.issn.0376-2491.2016.30.010

OBJECTIVE: To investigate the impact of placement in the procedures of gynecological laparoscopies or routine placement on the effects of levonorgestrel-releasing intrauterine system (LNG-IUS) for symptomatic adenomyosis in a prospective co…

nonrandomized-trial 2016
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2016.06.005

OBJECTIVE: To investigate treatment effects of levonorgestrel-releasing intrauterine system (LNG-IUS) for adenomyosis with menorrhea in a prospective study. METHODS: From December 2006 to December 2014, patients of symptomatic adenomyosis …

lab-animal 2016
Oncology letters ·doi:10.3892/ol.2016.4607

The aim of the present study was to investigate the effect and mechanism of different concentrations of aspirin in inhibiting the ovarian cancer of p53N236S gene knock-in mice. In total, 28 male p53S mice, with an age range of 4-6 weeks and…

meta-analysis 2016
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2016.06.003

The PvuII (C > T), XbaI (A > G) and (TA)n polymorphisms of ESR1 gene are potentially associated with susceptibility to endometriosis. A meta-analysis was conducted to evaluate comprehensively the associations between endometriosis and ESR1 …

other 2016
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2016.09.004

Objective: To investigate the changes of mestruation patterns and adverse effects during the treatment of levonorgestrel-releasing intrauterine system(LNG-IUS)for symptomatic adenomyosis in a prospective cohort study. Methods: From December…

rct 2016
Zhongguo zhen jiu = Chinese acupuncture & moxibustion

OBJECTIVE: To evaluate the effect and safety of acupuncture combined with Jiawei Mojie tablet for the prevention of endometriosis recurrence after surgery. METHODS: One hundred and six patients after the conservative surgery against endome…