Beasley TM — Endo Lab

2017

Caloric restriction improves health and survival of rhesus monkeys.

Nature communications ·doi:10.1038/ncomms14063

Caloric restriction (CR) without malnutrition extends lifespan and delays the onset of age-related disorders in most species but its impact in nonhuman primates has been controversial. In the late 1980s two parallel studies were initiated t…

2014

Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys.

Nature communications ·doi:10.1038/ncomms4557

Caloric restriction (CR) without malnutrition increases longevity and delays the onset of age-associated disorders in short-lived species, from unicellular organisms to laboratory mice and rats. The value of CR as a tool to understand human…

2012

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study.

Nature ·doi:10.1038/nature11432

Calorie restriction (CR), a reduction of 10–40% in intake of a nutritious diet, is often reported as the most robust non-genetic mechanism to extend lifespan and healthspan. CR is frequently used as a tool to understand mechanisms behind ag…

2009

Caloric restriction delays disease onset and mortality in rhesus monkeys.

Science (New York, N.Y.) ·doi:10.1126/science.1173635

Caloric restriction (CR), without malnutrition, delays aging and extends life span in diverse species; however, its effect on resistance to illness and mortality in primates has not been clearly established. We report findings of a 20-year …