Zhao S

This study aims to assess associations of dyslipidemia with in vitro fertilization/intracytoplasmic sperm injection outcomes in women undergoing their first ovarian stimulation and whether age, body mass index, or lipid levels modify these …

BACKGROUND: Endometriosis is a complex gynecological disorder lacking reliable biomarkers. This study aimed to identify core diagnostic genes through integrated computational approaches. Multiple endometriosis transcriptomic datasets were a…

OBJECTIVE: To compare the clinical efficacy of letrozole-induced ovulation cycles, natural cycles, and Hormonal Replacement Therapy cycle in frozen embryo transfer (FET), and to investigate the effects of different endometrial preparation p…

Endometriosis (EMS) is a chronic condition primarily characterized by pain and infertility, significantly affecting the physical, mental, and emotional well-being of patients. The primary goal of EMS treatment is to improve patients' qualit…

This study aimed to develop and validate a clinical prediction model for the success of the focused ultrasound ablation system (FUAS) in treating adenomyosis. A retrospective analysis was conducted on 250 patients from Qingdao Women and Chi…

PURPOSE: To investigate whether controlled ovarian stimulation (COS), as part of assisted reproductive technology (ART), accelerates the progression of BI-RADS categories. METHODS: This was a single-center, retrospective, propensity score …

OBJECTIVE: To quantitatively map and visualize global research trends, key contributors, and thematic evolution in fertility-preserving treatment for endometrial cancer from 2005 to 2024. METHODS: Research publications on fertility-preserv…

Endometriosis is a chronic gynecological disorder characterized by ectopic tissue growth and significant morbidity, yet current hormonal and surgical treatments often fail to prevent recurrence or entail severe side effects. Increasing evid…

OBJECTIVE: To evaluate the association of high-intensity focused ultrasound (HIFU) combined with syndrome differentiation-based individualized traditional Chinese medicine (TCM) herbal therapy with 12-month clinical outcomes compared with H…

Poor ovarian response (POR) constitutes a notable clinical challenge within the domain of assisted reproductive technology, primarily attributable to the lack of reliable biomarkers for precise diagnosis and treatment. This study reveals si…

PROBLEMS: To investigate the impact of anti-endometrial antibodies (EMAb) on pregnancy outcomes in infertile patients undergoing in vitro fertilization (IVF) and to assess the potential value of personalized treatment strategies. METHOD OF…

PURPOSE: This study aims to compare the live birth rate (LBR) and reproductive outcomes between gonadotropin-releasing hormone antagonist (GnRH-ant) and progestin-primed ovarian stimulation (PPOS) protocols in infertile women of advanced re…

BACKGROUND: The cytokines interleukin (IL)-6 and transforming growth factor-beta (TGF-β) are established inducers of pathogenic T helper 17 (Th17) cells from naïve T cells. In the maternal-fetal compartment, IL-6 signaling elevates levels o…

Blood-based liquid biopsies hold transformative potential for non-invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating…

For women with diminished ovarian reserve or of advanced age, controlled ovarian stimulation presents a significant challenge during in vitro fertilization cycles. This multi-center, open-label, randomized controlled trial enrolled 318 wome…

Endometriosis is a prevalent gynecological disorder characterized by chronic inflammation. Pyroptosis, a type of programmed proinflammatory cell death, plays a crucial role in various inflammatory diseases. However, its specific mechanism i…

BACKGROUND: To evaluate risk factors of overall survival (OS) in patients with advanced epithelial ovarian cancer (AEOC) and establish predictive models for predicting postoperative complete cytoreduction (R0 resection) in AEOC patients to …

OBJECTIVE: To evaluate the clinical efficacy of the combined technique involving Hem-o-lok clip closure of the uterine artery trunk and uterosacral ligament plication in laparoscopic complex hysterectomy. METHODS: A prospective study inclu…

Endometritis is a common inflammatory disorder of the female reproductive tract caused by microbial infection or immune dysregulation that impairs endometrial function and reproductive outcomes. Growing evidence indicates that programmed ce…

Endometriosis is a complex chronic inflammatory disease with an unclear etiology and limited treatment options, severely affecting the reproductive health and quality of life of many women. Histone deacetylases (HDACs), as key epigenetic re…

BACKGROUND: Benign ovarian tumor is a common clinical gynecological disease. Bilateral salpingo-oophorectomy is currently recommended for postmenopausal benign ovarian tumor, and whether the uterus needs to be removed simultaneously is cont…

BACKGROUND: The clinical benefit of immunotherapy in ovarian cancer (OC) remains limited. The primary reason is not simply a lack of immune activation, but rather the marked spatiotemporal heterogeneity of the tumour immune microenvironment…

BACKGROUND: Pyometra is an uncommon gynecologic disorder characterized by the accumulation of pus within the uterine cavity typically resulting from cervical obstruction. Spontaneous perforation of pyometra (SPP) is extremely rare but may r…

OBJECTIVE: To investigate the association of triglyceride-glucose index (TyG) and uric acid to high-density lipoprotein cholesterol ratio (UHR) with the prevalence of uterine fibroids (UF), and to evaluate the dose-response relationship and…

OBJECTIVES: To investigate the clinical characteristics of deep infiltrating endometriosis (DIE), summarize the experiences in its diagnosis and management, and identify potential peripheral blood indicators associated with the severity of …