Katherine F Roby

No ORCID on file · 4 papers in corpus
lab-animal 2024
Cell death & disease ·doi:10.1038/s41419-024-06717-3

Advanced epithelial ovarian cancer (EOC) survival rates are dishearteningly low, with ~25% surviving beyond 5 years. Evidence suggests that cancer stem cells contribute to acquired chemoresistance and tumor recurrence. Here, we show that IR…

other 2018
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-018-1151-3

PURPOSE: To assess expression of the histone demethylases KDM4A and KDM4B in granulosa collected from women undergoing oocyte retrieval and to determine if expression was related to pregnancy outcome. METHODS: Cumulus and mural granulosa c…

lab-animal 2015
Endocrinology ·doi:10.1210/en.2015-1397

In this report, we investigated the consequences of neonatal progesterone exposure on adult rat uterine function. Female pups were subcutaneously injected with vehicle or progesterone from postnatal days 3 to 9. Early progesterone exposure …

lab-animal 2014
Endocrinology ·doi:10.1210/en.2013-2150

Estrogens play pivotal roles in development and function of many organ systems, including the reproductive system. We have generated estrogen receptor 1 (Esr1)-knockout rats using zinc finger nuclease (ZFN) genome targeting. mRNAs encoding …