Tap WD

ORCID: 0000-0001-7779-2796 · 2 papers in corpus

2024

CSF1R Inhibition in Patients with Advanced Solid Tumors or Tenosynovial Giant Cell Tumor: A Phase I Study of Vimseltinib.

Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.ccr-24-0103

PurposeTenosynovial giant cell tumor (TGCT) is a locally aggressive neoplasm caused by dysregulation of the colony-stimulating factor 1 (CSF1) gene and overexpression of the CSF1 ligand. Surgery is the standard of care for most patients, bu…

2015

Molecular subtypes of uterine leiomyosarcoma and correlation with clinical outcome.

Neoplasia (New York, N.Y.) ·doi:10.1016/j.neo.2014.12.007

The molecular etiology of uterine leiomyosarcoma (ULMS) is poorly understood, which accounts for the wide disparity in outcomes among women with this disease. We examined and compared the molecular profiles of ULMS and normal myometrium (NL…