Qun Zhang

ORCID: 0000-0003-3590-757X · 4 papers in corpus
other 2019
miR-21 reverses impaired decidualization through modulation of KLF12 and NR4A1 expression in human endometrial stromal cells†
Biology of reproduction ·doi:10.1093/biolre/ioz026

Impaired decidualization has been considered a major cause of infertility in adenomyosis. However, the mechanism remains poorly understood. Recent studies suggest that microRNAs (miRNA) play a crucial role in embryo implantation. The aim of…

other 2016
Decreased expression of NR4A nuclear receptors in adenomyosis impairs endometrial decidualization
Molecular human reproduction ·doi:10.1093/molehr/gaw042

STUDY QUESTION: How do NR4A receptors drive decidualization of human endometrial stromal cells (hESCs)? SUMMARY ANSWER: NR4A receptors modulate endometrial decidualization by transcriptional activation of FOXO1A, and in adenomyosis patient…

article 2015
MicroRNA-181a is involved in the regulation of human endometrial stromal cell decidualization by inhibiting Krüppel-like factor 12
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-015-0019-y

BACKGROUND: The transformation of endometrium into decidua is essential for normal implantation of the blastocyst. However, the post-transcriptional regulation and the miRNAs involved in decidualization remain poorly understood. Here, we ex…

article 2013
CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-11-64

BACKGROUND: Matrix metalloproteinase 2 (MMP-2) has been reported to be an important regulator of cell migration and invasion through degradation of the extracellular matrix (ECM) in many diseases, such as cancer and endometriosis. Here, we …