Serpell LC

ORCID: 0000-0001-9335-7751 · 1 paper in corpus · active 2026
2026
Mechanism of Self-Assembly of the Gonadropin Releasing Hormone Antagonist Teverelix into Amyloid Fibrils.
Molecular pharmaceutics ·doi:10.1021/acs.molpharmaceut.5c00578

Teverelix is a short non-natural peptide, which is a gonadotropin releasing hormone antagonist and used as a treatment for prostate cancer. Teverelix is formulated as a trifluoroacetic acid salt, which, at the high concentrations used for p…