Xia Chen

ORCID: 0000-0002-0483-9474 · 7 papers in corpus
article 2026
Frontiers in microbiology ·doi:10.3389/fmicb.2026.1762444

BACKGROUND: Endometriosis (EMs) is a chronic inflammatory disease characterized by tumor-like growth behavior and limited therapeutic options. Increasing evidence suggests that gut microbiota may contribute to EMs progression by promoting c…

other 2025
Communications biology ·doi:10.1038/s42003-025-08617-4

Ovarian clear cell carcinoma (OCCC) represents a rare and aggressive subtype of epithelial ovarian cancer with distinctive clinical and molecular characteristics. However, the identification, origin, and molecular features of the malignant …

other 2025
Reproductive health ·doi:10.1186/s12978-025-02141-8

RESEARCH QUESTION: Does surgical management of ovarian endometriomas improve in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI)? DESIGN: This retrospective study analyzed 1,456 IVF/ICSI cycles from June 2017 to September …

other 2025
Nature communications ·doi:10.1038/s41467-025-66706-8

Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of…

article 2025
Human molecular genetics ·doi:10.1093/hmg/ddaf065

Mesenchymal cells constitute the primary structural support elements within endometriotic lesions, yet their pivotal roles in endometriotic pathogenesis remain largely uncharted. This study aimed to construct a single-cell atlas of endometr…

article 2024
Journal of Reproductive Immunology ·doi:10.1016/j.jri.2024.104312

BACKGROUND: Endometriosis (EMs) is a chronic disease characterized by endometrial-like tissue present outside of the uterus. Macrophages have been confirmed to participate in the development of EMs. Integrin β3 (ITGB3), a β-subunit of the i…

other 2019
The Journal of international medical research ·doi:10.1177/0300060519848928

OBJECTIVE: To investigate the effect of human chorionic gonadotropin (hCG) intrauterine injection before frozen–thawed embryo transfer (FET) in women with endometriosis. METHODS: This retrospective cohort study included 45 women with endom…