Rojas A

No ORCID on file · 4 papers in corpus · active 2012-2024

Study types

  • other 1

Condition tags

  • endometriosis 1
  • infertility 1
other 2024
[The Levels of Progesterone Receptors are Decreased in the Invasive Areas of the Recto-Vaginal Nodules of Endometriosis]
Revista medica de Chile ·doi:10.4067/s0034-98872024000700767

UNLABELLED: Endometriosis is a chronic disease characterized by the growth of the endometrium outside the uterine cavity. In response to estradiol, this tissue begins to proliferate and grow, forming lesions and nodules, which can invade th…

2022
Pharmacological antagonism of EP2 receptor does not modify basal cardiovascular and respiratory function, blood cell counts, and bone morphology in animal models.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie ·doi:10.1016/j.biopha.2022.112646

The EP2 receptor has emerged as a therapeutic target with exacerbating role in disease pathology for a variety of peripheral and central nervous system disorders. We and others have recently demonstrated beneficial effects of EP2 antagonist…

2020
Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models.
Journal of medicinal chemistry ·doi:10.1021/acs.jmedchem.9b01218

Activation of prostanoid EP2 receptor exacerbates neuroinflammatory and neurodegenerative pathology in central nervous system diseases such as epilepsy, Alzheimer's disease, and cerebral aneurysms. A selective and brain-permeable EP2 antago…

2012
Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype.
Biology of reproduction ·doi:10.1095/biolreprod.111.095885

Human endometrium regenerates on a cyclic basis from candidate stem/progenitors whose genetic programs are yet to be determined. A subpopulation of endometrial stromal cells, displaying key properties of mesenchymal stem cells (MSCs), has b…