Hidetaka Okada

ORCID: 0000-0002-7932-6999 · 10 papers in corpus · active 2001-2025

Study types

  • article 7
  • book-chapter 1
  • other 1
  • review 1

Condition tags

  • endometriosis 2
  • mesh:D004715 1
  • infertility 1
  • disambig:endometritis 1
article 2025
·doi:10.3390/nutraceuticals5030016

Endometrial stromal cells (EnSCs) undergo decidualization in response to progesterone. Decidualization facilitates spiral artery remodeling, immune tolerance in the endometrium, and fetal cell invasion and placentation—all essential for suc…

article 2023
·doi:10.3390/biomedicines11010210

The endometrium undergoes repeated proliferation and shedding during the menstrual cycle. Significant changes to this environment include fluctuations in the partial pressure of oxygen, exposure to a high-cytokine environment associated wit…

article 2019
·doi:10.1016/j.repbio.2019.02.005
review 2018
·doi:10.1002/rmb2.12088

BACKGROUND: Decidualization of the human endometrium, which involves a dramatic morphological and functional differentiation of human endometrial stromal cells (ESCs), is essential for the establishment of a successful pregnancy. Decidualiz…

other 2016
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2015.1121225

Recent evidence points to a possible role for hypoxia-inducible factor (HIF)-1 in the pathogenesis and development of endometriosis. The objectives of this study were to investigate the critical role of HIF-1 in endometriosis and the effect…

book-chapter 2016
·doi:10.1007/978-4-431-55972-6_6
article 2013
article 2012
·doi:10.3109/09513590.2012.736551

Stromal cell-derived factor-1 (SDF-1/CXCL12) and vascular endothelial growth factor (VEGF) are angiogenic factors that have possible roles in ovarian function. The objectives of this study were to investigate the association between the ind…

article 2009
·doi:10.1016/j.fertnstert.2009.08.056
article 2001
Molecular human reproduction ·doi:10.1093/molehr/7.4.341

Dienogest is a synthetic steroid that has been used as a progestogen in contraceptive pills and is currently being studied for its possible clinical use in the treatment of endometriosis. In this study, we investigated the direct effects of…