BACKGROUND: Endometriosis is a chronic gynecological disorder characterized by pain and impaired quality of life (QoL). While pharmacological and surgical options exist, their limitations necessitate complementary strategies. The comparativ…
Xiaojun Zheng,1,* Yu Wang,1,* Haiping Li,1 Juncha Zhang,1 Jun Liu,1 Xihui Zheng,1 Jie Zhang,1 Guangya Fan,1 Yi Sun,1 Bingxian Li,1 Jingyi Jiao,1 Guang Zuo,1 Xisheng Fan,1,2 Yanfen She1,2 1College of Acupuncture-Moxibustion and Tuina…
BACKGROUNDS: The levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective treatment for adenomyosis; however, its therapeutic benefits are frequently limited by a high expulsion risk. This study aimed to compare the safety and…
OBJECTIVE: Adenomyosis is a debilitating gynecologic condition. The present study aimed to compare the effects of laparoscopic total hysterectomy (LTH) and high-intensity focused ultrasound (HIFU) on pain relief, menstrual blood loss, and s…
ObjectiveTo compare the clinical efficacy of letrozole-induced ovulation cycles, natural cycles, and Hormonal Replacement Therapy cycle in frozen embryo transfer (FET), and to investigate the effects of different endometrial preparation pro…
BackgroundTo develop and validate a risk prediction model for malignant transformation in patients with gallbladder polyps (GBPs) using an interpretable machine learning framework and evaluate its predictive accuracy.MethodsA retrospective …
ObjectiveTo evaluate the cost-effectiveness of the levonorgestrel intrauterine system (LNG-IUS) compared with hysteroscopic niche resection (HNR) for women with niche-related postmenstrual spotting.DesignEconomic evaluation from a healthcar…
PurposeThe objective of this study was to investigate the cumulative pregnancy, cumulative live birth, and perinatal and obstetric outcomes of individuals in the POSEIDON group, with the aim of enhancing the management of individuals receiv…
IntroductionThe identification of severe acute pancreatitis (SAP) is paramount for effective patient management, but the gold standard for diagnosing SAP requires over 48 h of organ failure, which may delay timely treatment. Hence, this stu…
BackgroundsThe preoperative differentiation of borderline ovarian epithelial tumors (BOETs) remains challenging. While systemic inflammatory markers such as the platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and m…
PURPOSE: This paper provides a systematic review of the current applications of diffusion tensor imaging (DTI) in the imaging of pelvic floor-related anatomical structures and the assessment of microscopic pathological changes. METHODS: A …
BACKGROUND: Synchronous multiple primary malignancies (SMPMs) involving the uterus and ovary pose significant diagnostic challenges, particularly in distinguishing independent primary tumors from metastatic disease when tumors exhibit overl…
BackgroundSexually transmitted infections (STIs) contribute to female infertility by causing pelvic inflammatory disease (PID) and fallopian tube damage. Utilizing the Global Burden of Disease (GBD) database, we aim to comprehensively evalu…
BACKGROUND: Endometriosis is a chronic, estrogen-dependent inflammatory disorder that causes substantial pain and infertility. Observational studies have reported higher rates of multiple psychiatric disorders among individuals with endomet…
Study questionDoes ICSI improve the live birth rate in couples without severe male factor infertility compared to conventional IVF (cIVF)?Summary answerHigh-quality evidence showed no benefit of ICSI over cIVF in improving live birth or cum…
PurposeThe purpose of this experiment is to study the impact of dexmedetomidine combined with esketamine on postoperative fatigue in patients who undergo total laparoscopic hysterectomy.Patients and methodsA total of 176 patients who receiv…
BackgroundIn this study, we aimed to explore the effect of the timing of surgical management of hydrosalpinx on in vitro fertilization/intracytoplasmic single-sperm injection (IVF/ICSI) pregnancy outcomes in patients with tubal factor infer…
BACKGROUND: Acupuncture has been widely applied to polycystic ovarian syndrome (PCOS) patients. This network meta-analysis (NMA) aims to compare the effects of different acupuncture methods on PCOS from the aspects of hyperandrogenism, meta…
Objective: To evaluate the efficacy and safety of triptorelin acetate microspheres for injection compared with triptorelin acetate for injection in the treatment of endometriosis. Methods: A total of 392 patients with endometriosis were pro…
The aim of this study was to develop an advanced in vitro model of human endometrium using single-cell-derived endometrial epithelial organoids, enabling the study of embryo secretome-endometrial crosstalk at the maternal-fetal interface. S…
Endometriosis is a chronic estrogen-dependent gynecological disorder characterized by the ectopic growth of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of women of reproductive age worldwide. It is a lead…
Endometriosis diagnosis is often limited by the resolution of conventional imaging techniques (ultrasound/non-targeted MRI) as well as the invasiveness and recurrence risks associated with laparoscopy. To overcome these challenges, we devel…
Environmental estrogens, a group of exogenous endocrine-active compounds, are frequently present in animal feed, water, and husbandry environments. These compounds, which include synthetic xenoestrogens, phytoestrogens, and metalloestrogens…