Ravindra Mylvaganam

article 1989

Danazol therapy renders red cells resistant to osmotic lysis 1

FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fasebj.3.2.2914627

Danazol, an attenuated androgen, is useful in endometriosis, idiopathic thrombocytopenic purpura (ITP), and autoimmune hemolytic anemia (AIHA). However, its mechanism of action is unknown. We investigated the possibility that danazol affect…

article 1989

Long-Term Danazol Therapy in Autoimmune Thrombocytopenia: Unmaintained Remission and Age-Dependent Response in Women

·doi:10.7326/0003-4819-111-9-723

STUDY OBJECTIVE: To assess the long-term benefit and side effects of danazol therapy, and to delineate factors influencing the responses in patients with autoimmune thrombocytopenia. DESIGN: Before and after trial. SETTING: Referral-based h…

article 1989

Very Low Dose Danazol in Idiopathic Thrombocytopenic Purpura and its Role as an Immune Modulator

·doi:10.1097/00000441-198910000-00002

Danazol, an attenuated androgen, has been used successfully at its conventional dose (400-800 mg/day) in the treatment of idiopathic thrombocytopenic purpura (ITP). To minimize side effects, the authors tried a very low dose (50 mg/day) reg…

article 1985

Danazol Therapy for Autoimmune Hemolytic Anemia

·doi:10.7326/0003-4819-102-3-298

We evaluated the use of danazol in 15 patients with autoimmune hemolytic anemia of the warm antibody type. Danazol, 600 to 800 mg/d, was added to previous regimens or given initially in conjunction with high-dose prednisone treatment. Twelv…