Yi Gong

ORCID: 0000-0002-2348-9772 · 3 papers in corpus
article 2025
CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism
Journal of translational medicine ·doi:10.1186/s12967-025-06804-9

BACKGROUND: Fibrogenesis is a common pathological feature of endometriotic lesions and contributes to the development of endometriosis-associated chronic pelvic pain and infertility. TGF-β is a critical factor in the induction of fibrogenes…

article 2024
Lysine acetyltransferase 14 mediates TGF-β-induced fibrosis in ovarian endometrioma via co-operation with serum response factor
Journal of translational medicine ·doi:10.1186/s12967-024-05243-2

BACKGROUND: Fibrogenesis within ovarian endometrioma (endometrioma), mainly induced by transforming growth factor-β (TGF-β), is characterized by myofibroblast over-activation and excessive extracellular matrix (ECM) deposition, contributing…

preprint 2023
Exploration of  the mechanisms of Cyperi Rhizoma in the treatment of endometriosis through GEO datasets, network pharmacology, and molecular docking studies
·doi:10.21203/rs.3.rs-2667223/v1

AbstractCyperi rhizoma (CR) has traditionally been used to treat endometriosis (EMS), but its molecular mechanism remains unclear. To address this, we used a multi-faceted approach that included analysis of GEO datasets, network pharmacolog…