Zainab Basir

No ORCID on file · 10 papers in corpus · active 2003-2006

Study types

  • article 9
  • other 1

Condition tags

  • endometriosis 9
article 2006
Aberrant expression of deoxyribonucleic acid methyltransferases DNMT1, DNMT3A, and DNMT3B in women with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.05.077

ObjectiveSince endometriosis is a persistent disease with substantial gene dysregulation, there must be cellular memory of some sort that constitutes a unique cell identity for endometriotic cells. Epigenetic regulation, especially through …

article 2006
Genomic Alterations in Ectopic and Eutopic Endometria of Women with Endometriosis
Gynecologic and obstetric investigation ·doi:10.1159/000093130

BACKGROUND/AIMS: Ectopic and eutopic endometria of women with endometriosis have been shown to contain genomic alterations. In this study, we sought to identify genomic alterations in both ectopic and eutopic endometria of 5 women with endo…

article 2006
P-340
·doi:10.1016/j.fertnstert.2006.07.696
article 2006
Promoter Hypermethylation of Progesterone Receptor Isoform B (PR-B) in Endometriosis
Epigenetics ·doi:10.4161/epi.1.2.2766

The physiological effects of progesterone (P) are mediated by two isoforms of progesterone receptors (PRs): PR-A and PR-B. Progestins have long been used in the treatment of endometriosis but unfortunately the relief of pain is relatively s…

article 2005
Aberrant Expression of DNA Methyltransferases DNMT1 and DNMT3A in Endometriosis
·doi:10.1016/j.fertnstert.2005.07.304
article 2005
Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis
American Journal of Obstetrics and Gynecology ·doi:10.1016/j.ajog.2005.01.034

ObjectiveHOXA10, expressed in endometrium, plays an important role in uterine receptivity at the time of implantation. In the endometrium of women with endometriosis, its expression is reduced. The aim of this study was to determine whether…

article 2005
Further Evidence That Endometriosis May Originate From Genomic Alterations in the Eutopic Endometrium
·doi:10.1016/j.fertnstert.2005.07.491
article 2005
Transcriptional Characterizations of Differences between Eutopic and Ectopic Endometrium
Endocrinology ·doi:10.1210/en.2005-0426

Endometriosis, defined as the presence of endometrial glandular and stromal cells outside the uterine cavity, is a common gynecological disease with poorly understood pathogenesis. Using laser capture microdissection and a cDNA microarray w…

other 2004
Genomic alterations in the endometrium may be a proximate cause for endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2004.02.004

OBJECTIVE: To test the hypothesis that endometriosis may originate from genomic alterations in the endometrium by genomic analysis of endometrial tissues in patients with endometriosis and compare them with those from normal controls. METH…

article 2003
Resolution of clonal origins for endometriotic lesions using laser capture microdissection and the human androgen receptor (HUMARA) assay
Fertility and Sterility ·doi:10.1016/s0015-0282(02)04821-5

ObjectiveTo determine the clonal origins of endometriotic lesions using laser capture microdissection and PCR-based HUMARA assay.DesignMolecular genetic study of human tissue.SettingMolecular genetics laboratory in an academic setting.Patie…