Nina Hanke

No ORCID on file · 1 paper in corpus · active 2014

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2014
Inhibition of 17β-HSD1: SAR of bicyclic substituted hydroxyphenylmethanones and discovery of new potent inhibitors with thioether linker
European journal of medicinal chemistry ·doi:10.1016/j.ejmech.2014.05.074

Estradiol is the most potent estrogen in humans. It is known to be involved in the development and proliferation of estrogen dependent diseases such as breast cancer and endometriosis. The last step of its biosynthesis is catalyzed by 17β-h…