F Peter Guengerich

No ORCID on file · 2 papers in corpus
review 2020
Cytochrome P450 2E1 and its roles in disease
Chemico-biological interactions ·doi:10.1016/j.cbi.2020.109056

Cytochrome P450 (P450) 2E1 is the major P450 enzyme involved in ethanol metabolism. That role is shared with two other enzymes that oxidize ethanol, alcohol dehydrogenase and catalase. P450 2E1 is also involved in the bioactivation of a num…

review 2018
Human cytochrome P450 enzymes 5-51 as targets of drugs and natural and environmental compounds: mechanisms, induction, and inhibition - toxic effects and benefits
Drug metabolism reviews ·doi:10.1080/03602532.2018.1483401

Cytochrome P450 (P450, CYP) enzymes have long been of interest due to their roles in the metabolism of drugs, pesticides, pro-carcinogens, and other xenobiotic chemicals. They have also been of interest due to their very critical roles in t…