Sybil L. Crawford

Importance: Early menarche and early menopause are associated with increased risk of cardiovascular disease (CVD) in midlife, but little is known about the association between reproductive life span and the risk of CVD. Objective: To invest…

OBJECTIVE: To discover early hormonal predictors of menopause and the stages of the menopausal transition and to understand the hormonal basis behind the bleeding abnormalities common in the menopausal transition. METHODS: A cohort of 804 w…

Abstract This chapter reviews the factors at each stage of life that affect timing of the menopause, common urogenital disorders and the decision to have a hysterectomy, and the level of symptomatology experienced during the menopause trans…