Niraj R Joshi

No ORCID on file · 5 papers in corpus · active 2014-2023

Study types

  • article 4
  • other 1

Condition tags

  • endometriosis 5
  • endometrioma 1
  • die_deep_infiltrating 1
article 2023
JCI insight ·doi:10.1172/jci.insight.160815

The development and progression of endometriotic lesions are poorly understood, but immune cell dysfunction and inflammation are closely associated with the pathophysiology of endometriosis. There is a need for 3D in vitro models to permit …

article 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00228-0

Endometrial-like stromal cells, one of the main components of endometriotic lesions, are an important in vitro model for studying cellular and molecular mechanisms associated with lesion development in endometriosis. However, the short life…

other 2020
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgaa096

CONTEXT: NOTCH signaling is activated in endometriotic lesions, but the exact mechanisms remains unclear. IL-6, which is increased in the peritoneal fluid of women with endometriosis, induces NOTCH1 through E-proteins including E2A and HEB …

article 2016
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-2076

Context: Endometriosis results in aberrant gene expression in the eutopic endometrium (EuE) and subsequent progesterone resistance. MicroRNA (miR) microarray data in a baboon model of endometriosis showed an increased expression of miR-29c.…

article 2014
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2014-3720

CONTEXT: Endometriosis is a common gynecological disease affecting one in 10 women of reproductive age and is a major cause of pelvic pain and impaired fertility. Endometrial stromal cells of women with endometriosis exhibit a reduced respo…