Bradley R. Corr

BioID setup and proof-of-concept

UNLABELLED: Wnt ligand WNT4 is critical in female reproductive tissue development, with WNT4 dysregulation linked to related pathologies including breast cancer (invasive lobular carcinoma, ILC) and gynecologic cancers. WNT4 signaling in th…

The treatment for endometrial cancer is rapidly evolving with the development of molecular analysis and novel strategies. Surgical resection, cytotoxic chemotherapy, endocrine or hormonal treatment, and radiation have been the staples of tr…

Gynecologic malignancies, including ovarian cancer, endometrial cancer, and cervical cancer, affect hundreds of thousands of women worldwide every year. Wnt signaling, specifically Wnt/β-catenin signaling, has been found to play an essentia…

It is difficult to obtain enough human macrophages for extensive in vitro study, hence our relatively poor understanding of the mechanisms whereby human, as opposed to murine, macrophages kill tumours. Yet millions of macrophages are discar…