Seminara D

No ORCID on file · 3 papers in corpus · active 2014-2019
2019
Discovery of common and rare genetic risk variants for colorectal cancer.
Nature genetics ·doi:10.1038/s41588-018-0286-6

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome…

2017
The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.epi-16-0106

BackgroundCommon cancers develop through a multistep process often including inherited susceptibility. Collaboration among multiple institutions, and funding from multiple sources, has allowed the development of an inexpensive genotyping mi…

2014
Estimating the heritability of colorectal cancer.
Human molecular genetics ·doi:10.1093/hmg/ddu087

A sizable fraction of colorectal cancer (CRC) is expected to be explained by heritable factors, with heritability estimates ranging from 12 to 35% twin and family studies. Genome-wide association studies (GWAS) have successfully identified …