Aschard H

No ORCID on file · 1 paper in corpus · active 2022
2022
Portability of 245 polygenic scores when derived from the UK Biobank and applied to 9 ancestry groups from the same cohort.
American journal of human genetics ·doi:10.1016/j.ajhg.2021.11.008

The low portability of polygenic scores (PGSs) across global populations is a major concern that must be addressed before PGSs can be used for everyone in the clinic. Indeed, prediction accuracy has been shown to decay as a function of the …