Danielle J Sisnett

No ORCID on file · 28 papers in corpus · active 2022-2026

Study types

  • preprint 8
  • article 7
  • peer-review 7
  • other 3
  • review 2

Condition tags

  • endometriosis 28
  • chronic_pelvic_pain 15
  • infertility 15
  • endometrioma 1
  • adenomyosis 1
article 2022
Estrogen mediates inflammatory role of mast cells in endometriosis pathophysiology
Frontiers in immunology ·doi:10.3389/fimmu.2022.961599

Endometriosis is an estrogen dependent, chronic inflammatory disease characterized by the growth of endometrial lining outside of the uterus. Mast cells have emerged as key players in regulating not only allergic responses but also other me…

review 2022
Role of the endocannabinoid system in the pathophysiology of endometriosis and therapeutic implications
Journal of cannabis research ·doi:10.1186/s42238-022-00163-8

Endometriosis patients experience debilitating chronic pain, and the first-line treatment is ineffective at managing symptoms. Although surgical removal of the lesions provides temporary relief, more than 50% of the patients experience dise…

article 2022
T helper 17 axis and endometrial macrophage disruption in menstrual effluent provides potential insights into the pathogenesis of endometriosis
F&S science ·doi:10.1016/j.xfss.2022.04.007

OBJECTIVE: To identify immune cells, cytokines, and immune cell transcriptome in the menstrual effluent (ME) of women with endometriosis compared with that of healthy donors. DESIGN: Live immune cells were isolated from human ME samples an…