Ruyu Yang

No ORCID on file · 4 papers in corpus · active 2023-2026

Study types

  • article 2
  • other 2

Condition tags

  • endometriosis 4
  • chronic_pelvic_pain 1
  • die_deep_infiltrating 1
other 2026
CX3CR1/P2X4R signaling-mediated spinal microglial M1 polarization contributes to chronic pelvic pain in endometriosis
International immunopharmacology ·doi:10.1016/j.intimp.2026.116471

BACKGROUND: Deeply infiltrating endometriosis (DIE), characterized by its extrauterine invasion, is strongly associated with chronic pelvic pain (CPP). Peripheral-central sensitization synergistically contribute to the pathogenesis of CPP i…

other 2026
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2025.112721

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apop…

article 2024
Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization
International immunopharmacology ·doi:10.1016/j.intimp.2024.112559

BACKGROUND: Semaphorin 3A (Sema3A) is a member of neural guidance factor family well-known for inducing the collapse of nerve cell growth cone and regulating nerve redistribution. It also has been characterized as an immunoregulatory and tu…

article 2023
Gut dysbiosis-derived β-glucuronidase promotes the development of endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2023.03.032

OBJECTIVE: To explore the role of gut dysbiosis-derived β-glucuronidase (GUSB) in the development of endometriosis (EMs). DESIGN: 16S rRNA sequencing of stool samples from women with (n = 35) or without (n = 30) endometriosis and from a mo…