Various pathologies, environmental factors, and medications can cause anal distension. Sacrococcygeal chordoma is a rare tumor originating from the remnants of the primitive spinal cord. Nonetheless, only a few case reports of anal swelling…
INTRODUCTION: Menstruation marks a significant developmental milestone, typically indicating healthy and normal pubertal changes in females. Primary amenorrhea can arise from various causes, including outflow tract abnormalities, resistant …
Dietary factors have recently been recognized as potentially influential in the pathogenesis of endometriosis (EM), yet studies on the causal relationship between dietary preferences and EM are limited. The present study aimed to explore th…
BACKGROUND: Preimplantation embryos in vivo are exposed to various growth factors in the female reproductive tract that are absent in in vitro embryo culture media. Cell-free fat extract exerts antioxidant, anti-ageing, and ovarian function…
OBJECTIVE: Cesarean section (CS) rates have risen globally, with cesarean scar defect (CSD) being a common complication. Few studies have investigated the impact of CSD on in vitro fertilization/intracytoplasmic sperm injection frozen embry…
Serous papillary adenofibroma (SPAF) is a rare benign tumor in gynecological practice. Most patients have no symptoms and occasionally present with pelvic masses during physical examinations. SPAF consists of both fibrous and epithelial par…
Potassium permanganate (KMnO4) is a commercially available antiseptic used in bovine intrauterine lavage to manage postpartum infections. Lipopolysaccharides (LPS) are well-studied for their ability to induce inflammation and oxidative stre…
OBJECTIVE: The purpose of this study was to compare oral estradiol valerate and estradiol transdermal gel for clinical pregnancy outcomes in patients undergoing frozen-thaw embryo transfer (FET). METHODS: This was a prospective study perfo…
OBJECTIVE: To investigate the construction and clinical application value of Nomogram predictive model for recurrent spontaneous abortion (RSA) based on the expressions of MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1), miR…
[This corrects the article DOI: 10.3389/fimmu.2023.1115504.].
BACKGROUND: Premenstrual dysphoric disorder (PMDD) has been identified as a member of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5). The symptoms of premenstrual syndrome are uncertain, and these uncertain s…
PURPOSE: To investigate possible differences in cumulative live birth rates (CLBRs) among three progestins medroxyprogesterone acetate (MPA), dydrogesterone (DYG), and Progesterone within the progestin-primed ovarian stimulation (PPOS) prot…
Aging and neurodegenerative diseases are characterized by cognitive decline, impaired neuroplasticity, and epigenetic dysregulation. Curcumin, a bioactive polyphenol derived from Curcuma longa, has gained significant attention for its neuro…
Endometriosis (EMS) is a benign gynecological disease characterized by the growth of endometrial tissue outside the uterine cavity. Evidence shows that the survival of patients with ectopic endometrial implants is associated with a dysregul…
Diabetic kidney disease (DKD) is recognized as one of the leading causes of chronic kidney disease (CKD) and end-stage kidney disease (ESKD) worldwide, representing a rapidly growing global public health concern. Despite significant advance…
Alternative polyadenylation (APA) is a critical post-transcriptional regulatory mechanism, yet its role in follicular development and atresia in waterfowl remains poorly understood. To address this, we performed full-length transcriptome se…
INTRODUCTION: Thin endometrium poses a major therapeutic challenge in assisted reproductive technologies by compromising pregnancy success and live birth outcomes. A substantial proportion of patients remain refractory to existing therapies…
BACKGROUND: This study aimed to observe the effect of dexmedetomidine on the median effective concentration (EC50) of ropivacaine for postoperative analgesia in ultrasound-guided transversus abdominis plane block. METHODS: Patients undergo…
OBJECTIVE: To evaluate the efficacy and safety of the Peiyu Granules (PYG) compared with placebo on early miscarriage rates among women undergoing embryo transfer. METHODS: A double-blind, parallel-group randomized clinical trial between F…
BACKGROUND: Current advances in high-throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutatio…
BACKGROUND: Chronic pain afflicts approximately 20% of the global adult population and is frequently undertreated, with available pharmacologic options often associated with significant long-term adverse effects. Although omega-3 fatty acid…
INTRODUCTION: To investigate the effect of high-dose estrogen and progesterone sequential assisted hysteroscopic cold knife separation surgery on the recovery of uterine cavity morphology in patients with severe intrauterine adhesions (IUA)…
Extracellular vesicles (EVs) are secreted from biological cells and contain many molecules with diagnostic values or therapeutic functions. There has been great interest in academic and industrial communities to utilize EVs as tools for dia…
Ovarian cancer remains one of the most lethal gynecologic malignancies, often marked by late-stage diagnosis and resistance to conventional therapies. Poly (ADP-ribose) polymerase (PARP) inhibitors have significantly advanced treatment, par…