Linda Williams

ORCID: 0000-0002-6317-1718 · 7 papers in corpus
rct 2026
ESPriT1: the effectiveness of laparoscopic treatment of isolated superficial peritoneal endometriosis for managing chronic pelvic pain in women: a randomised controlled feasibility trial
Reproduction & fertility ·doi:10.1530/raf-26-0043

Endometriosis is a chronic pain condition that affects >190 million people worldwide. It is recommended in clinical guidelines to remove the most common type of endometriosis, 'superficial peritoneal endometriosis' (SPE), if it is diagnosed…

article 2025
Dichloroacetate for the treatment of endometriosis-associated pain (EPiC1): a single-arm feasibility study
·doi:10.1016/j.lanogw.2025.100028
article 2023
Effectiveness of laparoscopic removal of isolated superficial peritoneal endometriosis for the management of chronic pelvic pain in women (ESPriT2): protocol for a multi-centre randomised controlled trial
Trials ·doi:10.1186/s13063-023-07386-x

BACKGROUND: Endometriosis affects 190 million women and those assigned female at birth worldwide. For some, it is associated with debilitating chronic pelvic pain. Diagnosis of endometriosis is often achieved through diagnostic laparoscopy.…

other 2021
Dichloroacetate as a possible treatment for endometriosis-associated pain: a single-arm open-label exploratory clinical trial (EPiC)
Pilot and feasibility studies ·doi:10.1186/s40814-021-00797-0

BACKGROUND: Endometriosis (where endometrial-like tissue is found outside the uterus) affects ~ 176 million women worldwide and can lead to debilitating pelvic pain. There is an unmet need for new medical treatment options for endometriosis…

article 2020
A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1)
PloS one ·doi:10.1371/journal.pone.0227695

BACKGROUND: Endometriosis is defined by the presence of endometrial-like tissue (lesions) outside the uterus, commonly on the pelvic peritoneum. It affects 6-10% of women and is associated with debilitating pelvic pain. Current management o…

erratum 2020
Correction: A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1)
PloS one ·doi:10.1371/journal.pone.0230055

[This corrects the article DOI: 10.1371/journal.pone.0227695.].

article 2018
A pilot randomised double blind controlled trial of the efficacy of purified fatty acids for the treatment of women with endometriosis-associated pain (PurFECT): study protocol
Pilot and feasibility studies ·doi:10.1186/s40814-018-0274-8

BACKGROUND: Endometriosis affects 6-10% of women and is associated with debilitating pelvic pain. It costs the UK > £2.8 billion per year in loss of productivity. Endometriosis can be managed by surgical excision or medically by ovarian sup…