Jun Gu

No ORCID on file · 3 papers in corpus
lab-animal 2020
In vivo Screening of Natural Products Against Angiogenesis and Mechanisms of Anti-Angiogenic Activity of Deoxysappanone B 7,4'-Dimethyl Ether
Drug design, development and therapy ·doi:10.2147/dddt.s252681

INTRODUCTION: The aim of this study was to screen the leading compounds of natural origin with anti-angiogenic potential and to investigate their anti-angiogenic mechanism preliminarily. MATERIALS AND METHODS: An initial screening of 240 c…

lab-animal 2018
Identification of mundoserone by zebrafish in vivo screening as a natural product with anti-angiogenic activity
Experimental and therapeutic medicine ·doi:10.3892/etm.2018.6748

The present study aimed to screen natural products with anti-angiogenic potential from the Natural Products Collection of MicroSource. The anti-angiogenic activity of 240 natural products was assessed using the zebrafish line Tg(fli1a: EGFP…

observational 2018
The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese
Aging ·doi:10.18632/aging.101461

Copy number variations (CNVs) have been shown to cause numerous diseases, however, their roles in human lifespan remain elusive. In this study, we investigate the association of CNVs with longevity by comparing the Han Chinese genomes of lo…