Provencher D

No ORCID on file · 3 papers in corpus
other 2017
Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes
Nature genetics ·doi:10.1038/ng.3849

We studied the whole-genome point mutation and structural variation patterns of 133 tumors (59 high-grade serous (HGSC), 35 clear cell (CCOC), 29 endometrioid (ENOC), and 10 adult granulosa cell (GCT)) as a substrate for class discovery in …

article 2015
The ARID1A pathway in ovarian clear cell and endometrioid carcinoma, contiguous endometriosis, and benign endometriosis
International Journal of Gynecology & Obstetrics ·doi:10.1016/j.ijgo.2015.02.021

OBJECTIVE: To assess ARID1A-encoded protein (BAF250a) and phosphorylated AKT (pAKT) expression, apoptosis, and the DNA damage response pathway in endometrioid and clear cell ovarian cancers (endometriosis-associated ovarian cancers [EAOCs])…

article 2010
ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
The New England journal of medicine ·doi:10.1056/nejmoa1008433

BACKGROUND: Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis, but the molecular events involved in this transformation have not been described. METHODS: We sequenced the whole transcriptomes of 18 ovarian clear-ce…