Kovács R

ORCID: 0000-0003-3946-2424 · 3 papers in corpus · active 2020-2022
2022
In Vivo Efficacy of Amphotericin B against Four Candida auris Clades.
Journal of fungi (Basel, Switzerland) ·doi:10.3390/jof8050499

Candida auris is a multidrug-resistant fungus against which in some clinical situations amphotericin B (AMB) remains the alternative or first line drug. We compared daily 1 mg/kg of AMB efficacy in a neutropenic murine bloodstream infection…

2020
Comparison of in vivo pathogenicity of four Candida auris clades in a neutropenic bloodstream infection murine model.
Emerging microbes & infections ·doi:10.1080/22221751.2020.1771218

Candida auris is an emerging worldwide concern, but comparative data about the virulence of different C. auris lineages in mammalian hosts is lacking. Different isolates of the four prevalent C. auris clades (South Asian n = 5, East Asian n…

2020
Differences in the sensitivity of classically and alternatively activated macrophages to TAK1 inhibitor-induced necroptosis.
Cancer immunology, immunotherapy : CII ·doi:10.1007/s00262-020-02623-7

Controlling the balance of pro-inflammatory M1 versus anti-inflammatory M2 macrophages may have paramount therapeutic benefit in cardiovascular diseases, infections, cancer and chronic inflammation. The targeted depletion of different macro…