Serkan Yıldırım

ORCID: 0000-0003-2457-3367 · 3 papers in corpus
article 2023
The Effects of Some Phosphodiesterase 5 Inhibitors on Oxidative Stress, VEGF, BMP 2 and 9 in the Liver Tissue of Ovariectomized Rats
·doi:10.5505/vtd.2023.90757

Introduction:Osteoporosis is an important health problem and there is no effective treatment yet.phosphodiesterase 5 inhibitors are promising agents for the treatment of osteoporosis.In this study, we aimed to determine the effects of phosp…

dataset 2022
Do avanafil and zaprinast exert positive effects on bone tissue via the nitric oxide/cyclic guanosine monophosphate/protein kinase-G signaling pathway in rats with ovariectomy-induced osteoporosis?
·doi:10.6084/m9.figshare.19923842

Phosphodiesterase-5 inhibitors (PDE-5Is) exert positive effects on bone healing and mineralization by activation the nitric oxide/cyclic guanosine monophosphate/protein kinase-G (NO/cGMP/PKG) signaling pathway. In this study, the effects of…

article 2020
Stimulating effects of vardenafil, tadalafil, and udenafil on vascular endothelial growth factor, angiogenesis, vitamin D3, bone morphogenic proteins in ovariectomized rats
·doi:10.1080/13813455.2020.1755695

Objective This study investigated the effect of vardenafil, tadalafil, and udenafil from phosphodiesterase-5 inhibitors (PDE-5Is) on bone morphogenic-protein (BMP)2 and 4 levels, along with angiogenesis in ovariectomized rat’s kidney.Method…