Angela N. Pierce

ORCID: 0000-0003-2420-6364 · 4 papers in corpus
review 2022
Clinical Review of Neuromusculoskeletal Complementary and Alternative Approaches for the Treatment of Chronic Pelvic Pain Syndrome
Cureus ·doi:10.7759/cureus.27077

Chronic pelvic pain syndrome (CPPS) is a functional pain disorder characterized by ongoing pain in the apparent absence of clinically identifiable causes. The prevalence of functional pain disorders demonstrates the importance of adequate m…

lab-animal 2021
Voluntary wheel running improves outcomes in an early life stress-induced model of urologic chronic pelvic pain syndrome in male mice
Pain ·doi:10.1097/j.pain.0000000000002178

Patients with a history of early life stress (ELS) exposure have an increased risk of developing chronic pain and mood disorders later in life. The severity of ELS in patients with urologic chronic pelvic pain syndrome (UCPPS) is directly c…

lab-animal 2015
Neonatal maternal separation in mice as a pre-clinical model for female chronic pelvic pain

Chronic pelvic pain is currently estimated to impact 9.2 million women in the United States. As many as half of these women will have comorbid conditions, such as chronic pain in multiple pelvic organs, mood disorder, and/or somatic functio…

lab-animal 2014
Vaginal hypersensitivity and hypothalamic-pituitary-adrenal axis dysfunction as a result of neonatal maternal separation in female mice
Neuroscience ·doi:10.1016/j.neuroscience.2014.01.022

Early life stress can permanently alter functioning of the hypothalamic-pituitary-adrenal (HPA) axis, which regulates the stress response and influences the perception of pain. Chronic pelvic pain patients commonly report having experienced…