Dawn R. Cochrane

No ORCID on file · 8 papers in corpus · active 2017-2020

Study types

  • article 6
  • other 2

Condition tags

  • endometriosis 8
article 2020
·doi:10.1158/1557-3265.ovca19-b09

Abstract Endometrial epithelium gives rise to both endometrial and ovarian cancers (of clear-cell and endometrioid subtypes), the latter arising from ectopic endometrium (endometriosis). Endometrial epithelium comprises mainly secretory cel…

article 2019
·doi:10.1158/1557-3265.ovcasymp18-gmm-020

Abstract Both clear cell ovarian carcinoma (CCOC) and endometrioid ovarian carcinoma (ENOC) are associated with ovarian endometriotic cysts, which is believed to be their precursor lesion. However, genomic evidence is lacking which could ex…

article 2018
·doi:10.1158/1557-3265.ovca17-b22

Abstract Endometrioid ovarian cancer (ENOC) and clear cell ovarian cancer (CCOC) share a common precursor lesion, endometriosis (ectopic growth of uterine lining), hence the designation endometriosis-associated ovarian cancer (EAOC). Women …

article 2018
·doi:10.1158/1557-3265.ovca17-b39

Abstract Both clear cell ovarian carcinoma (CCOC) and endometrioid ovarian carcinoma (ENOC) are associated with ovarian endometriotic cysts, which is believed to be the precursor lesion of these cancers. Women with endometriotic cysts have …

article 2017
·doi:10.1158/1557-3265.ovcasymp16-dpoc-014

Abstract PURPOSE: Women with endometriosis, a painful condition caused by displaced endometrial tissue, have a 3-fold increased risk of developing endometrioid ovarian cancer (ENOC) and clear cell ovarian cancer (CCOC). How two distinct can…

other 2017
The Journal of Pathology ·doi:10.1002/path.4934

Endometrial epithelium is the presumed tissue of origin for both eutopic and endometriosis-derived clear cell and endometrioid carcinomas. We had previously hypothesized that the morphological, biological and clinical differences between th…

other 2017
Nature genetics ·doi:10.1038/ng.3849

We studied the whole-genome point mutation and structural variation patterns of 133 tumors (59 high-grade serous (HGSC), 35 clear cell (CCOC), 29 endometrioid (ENOC), and 10 adult granulosa cell (GCT)) as a substrate for class discovery in …

article 2017
Gynecologic oncology ·doi:10.1016/j.ygyno.2017.09.032